Chemoimmunotherapy for canine lymphosarcoma

Canine Lymphosarcoma : Diagnosis and Treatment

This article discusses the diagnostic and treatment approach to canine lymphosarcoma (LSA). Several conclusions can be drawn from the extensive body of studies on canine LSA in clinical and pathologic medicine: It is now recognized that this disease has great clinical and histologic heterogeneity; in most cases, survival can be improved with combination chemotherapy; and drug resistance is a ma...

Chemoimmunotherapy for advanced gastrointestinal carcinomas

The combination of a single low dose of cyclophosphamide (Cy) with the adenovirus-mediated gene transfer of interleukin-12 (AdIL-12) might represent a successful therapy for experimental gastrointestinal tumors. This approach has been proven to revert immunosuppressive mechanisms elicited by cancer cells and to synergistically promote antitumor immunity. In addition, this therapeutic regimen ha...

Induction chemoimmunotherapy.

Uveal lymphosarcoma.

LYMPHOMATOUS tumours involving the lids and orbit have been recognized and repeatedly reported in the literature for many years; intra-ocular involvement on the contrary is rare if the lymphomatous infiltrations associated with lymphatic leukaemia are excluded. Kukain (1935) and Triebenstein (1920) have each described a case of uveal lymphosarcoma complicated by secondary glaucoma, and other is...

Studies of marrow transplantation, chemotherapy and cross-circulation in canine lymphosarcoma.